) BLutein™ Dyes | Bausch + Lomb Surgical

Introducing BLuteinTM Dyes: The complete ophthalmic dye range designed to help free you from safety profile concerns

The BLuteinTM range consists of dyes for both posterior segment staining and anterior capsule staining, so you always have a dye that meets your surgical needs

The BLuteinTM Dyes all contain naturally sourced lutein
• Lutein is a pigment physiologically present in the human retina, known to be important
for overall eye health5-8


Lutein may also help protect the retina during surgery by:
• Absorbing damaging blue light before it reaches retinal cells through its blue light filter action9, 10
• Acting as an antioxidant to neutralise free radicals that may be harmful to retinal cells11-13
• Reducing iatrogenic stress to the retinal tissue allowing faster functional recovery after surgery14

The BLutein™ Dyes for ILM and ERM staining also contain highly pure PBB® 15-17

The BLutein™ Vitreo Lutein Vitreous Staining Dye

• 2% crystalline Lutein

Designed to:
• Improve visualisation of the vitreous during surgery

With the aim of:
• Reducing surgery time
• Minimising risk of complications

The BLutein™ Single Lutein Blue ILM Staining Dye

• 1% soluble Lutein
• 0.05% PBB®

Designed to:
• Provide precise identification of the ILM during surgery
• Improve visualisation of the ILM

With the aim of:
• Reducing surgery time
• Minimising risk of complications

The BLutein™ Double Lutein Blue ILM and ERM Staining Dye

• 2% soluble Lutein
• 0.05% PBB®
• 0.15% trypan blue

Designed to:
• Provide precise identification of the ILM and ERM during surgery
• Improve visualisation during surgery

With the aim of:
• Reducing surgery time
• Minimising risk of complications

The BLutein™ Phaco Lutein Anterior Capsule Staining Dye

• 1% soluble Lutein
• 0.04% trypan blue

Designed to:
• Provide optimal anterior capsule staining for cataract surgeries
• Facilitate visualisation of the anterior lens capsule
• Facilitate continuous curvilinear capsulorhexis

References

1. Bergamo VC et al., Asia Pac J Ophthalmol (Phila). 2021; 10: 26-38.
2. Rodrigues EB et al., Am J Ophthalmol. 2010; 149: 265-77.
3. Casaroli-Marano RP et al., Curr Eye Res. 2015; 40: 707-718.
4. Morales MC et al., Invest Ophthalmol Vis Sci. 2010; 51: 6018-6029.
5. Buscemi S et al., Nutrients. 2018; 10: 1321.
6. Bernstein PS et al., Prog Retin Eye Res. 2016; 50: 34-66.
7. Lima VC et al., Int J Retin Vitr. 2016; 2:19.
8. Beccera MO et al., J Funct Foods. 2020; 66: 103771.
9. Junghans A et al., Arch Biochem Biophys. 2001; 391:160-164.
10. Sasaki M et al., J Nutr Biochem. 2012; 23: 423-429.
11. Bian Q et al., Free Radic Biol Med. 2012; 53: 1298-1307.
12. Sundelin SP et al., Free Radic Biol Med. 2001; 31: 217-225.
13. Kim SR et al., Exp Eye Res. 2006; 82: 828-839.
14. Romano MR et al., Graefes Arch Clin. Exp Ophthalmol. 2018; 256: 1573-1580.
15. European Patent EP 3 692 101 B1.
16. Spadaro A et al., Frontiers Pharmacol. 2020; 11: 708.
17. Bucolo C et al., Poster #39-A0113. Presented at ARVO Annual Meeting 2019.


Please read the Instructions for Use (IFU) / Directions for Use (DFU) for important product use and safety information for BLutein™ Dyes.
©2023 Bausch + Lomb Incorporated or its affiliates ©/™ are trademarks of Bausch & Lomb Incorporated or its affiliates. DYE INT BLutein Dyes Brochure_052023_01.

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